Antifungal Effect of Henna (Lawsonia inermis) Extract on Pathogenic Fungi

The study aimed at undertaking preliminary phytochemical studies and antifungal activities of Lawsonia inermis leaf extracts against clinical Candida isolates from female patients attending Dalhatu Araf Specialist Hospital (DASH) Lafia, Nasarawa State. HVS (High Vaginal Swab) samples were collected 185 subjects transported to the laboratory for analysis. Microbial culture isolations done on Sabouraud dextrose agar (SDA), Blood agar, Potato (PDA) broth. Identification was following standard guideline identification including microscopic, cultural biochemical characteristics (sugar utilization fermentation). Antifungal susceptibility tests plant different concentrations carried out isolates. Distilled water ketoconazole drug served as negative positive control respectively. Zones inhibitions, minimum inhibitory concentration (MIC) fungicidal (MFC) determined. Data analysed Minitab 16.0 software descriptive (mean with error) inferential statistics Chi Square 95% confidence limit. In conclusion, L.inermis has been shown have properties since it contained quality phytochemicals in sufficient quantity that may be explored synthesis drugs some species Candida. This finding is crucial management candidiasis study.